The c6g.12xlarge is a compute-optimized AWS EC2 instance: 48 vCPU and 96 GiB of memory, 2.00 GiB per vCPU. In the name, "c" stands for compute, "6" is the generation, "g" marks AWS Graviton (ARM) processors and "12xlarge" is the size within the c6g family. It runs on AWS Graviton2 Processor at 2.5 GHz, and AWS introduced it in June 2020. AWS has since shipped c7g, c8g and c9g; c7g.12xlarge is the direct replacement at this size, scoring 1,252,038 CoreMark/s against this instance's 920,775 — roughly 36% more throughput for the same vCPU count. No single Spot node covers 48 vCPU and 96 GiB, so the equivalent is a fleet: 3 × ch.vs1.2xlarge, 48 vCPU and 96 GiB in total, about 92% below the US East (N. Virginia) on-demand rate. Spot delivers compute as managed Kubernetes, so a node pool of that size is the native shape of the answer rather than a workaround — provided the workload scales horizontally.
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c6g.12xlarge gives you 48 vCPU and 96 GiB in a single machine. The largest comparable Spot node, ch.vs1.2xlarge, is 16 vCPU and 32 GiB, so the equivalent here is 3 nodes rather than one.
Spot runs as managed Kubernetes, so a 3-node pool is the normal way to run things rather than a workaround. If your workload already sits behind a load balancer, a queue or a scheduler, it spreads across them without changes. If it needs all 48 cores and 96 GiB in one process, it does not.
x86_64 onlyc6g.12xlarge is Graviton (arm64) and Rackspace Spot has no arm64 nodes, so you'd be moving to x86. You'll need x86 builds of your images, and per-core speed differs between the chips — worth testing before you decide how many nodes to run.